Elevated intrasynaptic dopamine release in Tourette's syndrome measured by PET.

Singer, Harvey S; Szymanski, Sally; Giuliano, Joseph; Yokoi, Fuji; Dogan, A Semih; Brasic, James R; Zhou, Yun; Grace, Anthony A; Wong, Dean F

Singer, Harvey S; Szymanski, Sally; Giuliano, Joseph; Yokoi, Fuji; Dogan, A Semih; Brasic, James R; Zhou, Yun; Grace, Anthony A; Wong, Dean F.

Affiliation

Singer HS; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

Am J Psychiatry ; 159(8): 1329-36, 2002 Aug.

Article in En | MEDLINE | ID: mdl-12153825

Subject(s)

Corpus Striatum/metabolism; Dopamine/metabolism; Tourette Syndrome/metabolism; Adult; Amphetamine/administration & dosage; Amphetamine/pharmacology; Corpus Striatum/diagnostic imaging; Corpus Striatum/physiopathology; Dopamine/physiology; Dopamine Antagonists; Humans; Injections, Intravenous; Male; Middle Aged; Putamen/diagnostic imaging; Putamen/metabolism; Putamen/physiopathology; Raclopride; Sodium Chloride/administration & dosage; Sodium Chloride/pharmacology; Synapses/diagnostic imaging; Synapses/drug effects; Synapses/metabolism; Tomography, Emission-Computed/methods; Tomography, Emission-Computed/statistics & numerical data; Tourette Syndrome/diagnostic imaging; Tourette Syndrome/physiopathology

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Collection: 01-internacional Database: MEDLINE Main subject: Dopamine / Tourette Syndrome / Corpus Striatum Limits: Adult / Humans / Male / Middle aged Language: En Journal: Am J Psychiatry Year: 2002 Document type: Article Affiliation country: United States Country of publication: United States

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