Increase of immunoglobulin productivity of human-human hybridoma HB4C5 cells by histone.

Okamoto, Takeaki; Sugahara, Takuya; Tachibana, Hirofumi; Yamada, Koji

Okamoto, Takeaki; Sugahara, Takuya; Tachibana, Hirofumi; Yamada, Koji.

Affiliation

Okamoto T; Department of Bioscience and Biotechnology, Graduate School of Kyushu University, Hakozaki, Fukuoka, Japan.

Biosci Biotechnol Biochem ; 66(6): 1241-5, 2002 Jun.

Article in En | MEDLINE | ID: mdl-12162544

Subject(s)

Histones/pharmacology; Hybridomas/drug effects; Hybridomas/metabolism; Immunoglobulin M/biosynthesis; Animals; B-Lymphocytes/drug effects; B-Lymphocytes/metabolism; Burkitt Lymphoma/immunology; Burkitt Lymphoma/metabolism; Cattle; Chymotrypsin/metabolism; Dose-Response Relationship, Drug; Flow Cytometry; Histones/administration & dosage; Histones/chemistry; Histones/metabolism; Humans; Multiple Myeloma/immunology; Multiple Myeloma/metabolism; Protein Binding; Protein Conformation; Protein Transport; Thymus Gland; Trypsin/metabolism; Tumor Cells, Cultured

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Collection: 01-internacional Database: MEDLINE Main subject: Immunoglobulin M / Histones / Hybridomas Limits: Animals / Humans Language: En Journal: Biosci Biotechnol Biochem Journal subject: BIOQUIMICA / BIOTECNOLOGIA Year: 2002 Document type: Article Affiliation country: Japan Country of publication: United kingdom

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