Pharmacokinetic and pharmacodynamic analysis of TS-943, a selective non-peptide platelet glycoprotein-IIb/IIIa (GPIIb/IIIa) receptor antagonist, using a nonlinear mixed effect model in dogs.

Furuya, A; Nozawa, M; Gotoh, J; Jingu, S; Akimoto, M; Higuchi, S; Suwa, T; Ogata, H

Furuya, A; Nozawa, M; Gotoh, J; Jingu, S; Akimoto, M; Higuchi, S; Suwa, T; Ogata, H.

Affiliation

Furuya A; Research Center, Taisho Pharmaceutical Co, Ltd, Saitama, Japan. atsushi.furuya@po.rd.taisho.co.jp

J Pharm Pharmacol ; 54(7): 921-7, 2002 Jul.

Article in En | MEDLINE | ID: mdl-12162710

Subject(s)

Amidines/pharmacology; Amidines/pharmacokinetics; Platelet Glycoprotein GPIIb-IIIa Complex/antagonists & inhibitors; Thiazoles/pharmacology; Thiazoles/pharmacokinetics; Amidines/administration & dosage; Animals; Dogs; Humans; Infusions, Intravenous; Injections, Intravenous; Male; Platelet Aggregation/drug effects; Thiazoles/administration & dosage

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Collection: 01-internacional Database: MEDLINE Main subject: Thiazoles / Platelet Glycoprotein GPIIb-IIIa Complex / Amidines Limits: Animals / Humans / Male Language: En Journal: J Pharm Pharmacol Year: 2002 Document type: Article Affiliation country: Japan Country of publication: United kingdom

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