Total synthesis of deamido bleomycin a(2), the major catabolite of the antitumor agent bleomycin. | J Am Chem Soc;124(32): 9476-88, 2002 Aug 14. | MEDLINE

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Total synthesis of deamido bleomycin a(2), the major catabolite of the antitumor agent bleomycin.

Zou, Ying; Fahmi, Nour Eddine; Vialas, Corine; Miller, Guy M; Hecht, Sidney M.

Affiliation

Zou Y; Contribution from the Department of Chemistry, University of Virginia, Charlottesville 22901, USA.

J Am Chem Soc ; 124(32): 9476-88, 2002 Aug 14.

Article in En | MEDLINE | ID: mdl-12167044

Subject(s)

Antibiotics, Antineoplastic/chemical synthesis; Bleomycin/chemical synthesis; Antibiotics, Antineoplastic/metabolism; Bleomycin/metabolism; Humans; Hydrolases/metabolism

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Collection: 01-internacional Database: MEDLINE Main subject: Bleomycin / Antibiotics, Antineoplastic Limits: Humans Language: En Journal: J Am Chem Soc Year: 2002 Document type: Article Affiliation country: United States Country of publication: United States

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Collection: 01-internacional Database: MEDLINE Main subject: Bleomycin / Antibiotics, Antineoplastic Limits: Humans Language: En Journal: J Am Chem Soc Year: 2002 Document type: Article Affiliation country: United States Country of publication: United States