Acute changes in dopamine release and turnover in rat caudate nucleus following a single dose of methamphetamine.
J Neural Transm (Vienna)
; 109(9): 1151-8, 2002 Sep.
Article
in En
| MEDLINE
| ID: mdl-12203042
ABSTRACT
Acute changes in dopamine (DA) turnover were studied in the caudate nucleus (CN) of adult male rats between 0-24 h after a single injection of Methamphetamine (20 mg/kg, ip). A single dose of METH-induced an increase in DA turnover [(DOPAC + HVA)/DA] concomitant with an acute DA release followed by transient DA and DOPAC depletion in the rat CN.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Dopamine
/
Caudate Nucleus
/
Presynaptic Terminals
/
Dopamine Uptake Inhibitors
/
Amphetamine-Related Disorders
/
Methamphetamine
Limits:
Animals
Language:
En
Journal:
J Neural Transm (Vienna)
Year:
2002
Document type:
Article
Affiliation country:
United States