[Effects of heat and noise environments on lipid peroxidation erythrocyte membrane in pilots].

ABSTRACT

OBJECTIVE: To investigate the effects of heat and noise environments on lipid peroxidation of erythrocyte membrane in pilots. METHOD: Twenty-four pilots and twenty-one ground personnel (control group) served as the subjects. The pilots performed flying in heat and noise environments. Glutathione peroxidase (GSHpx) and malondialdehyde [correction of malondiadehyde] (MDA) levels in erythrocyte membrane were determined before flying (600 a.m.), immediately after flying (1200 a.m.) and 8 hours after flying (800 p.m.) respectively with a spectrophotometer. RESULT: Immediately after flying, GSHpx activity in pilot's erythrocyte membrane decreased significantly as compared with that in control group. Immediately after flying and 8 h after flying, MDA contents in pilots increased significantly as compared with that of control group. CONCLUSION: Heat and noise environments might induce increase of lipid peroxidation reaction and decrease of antioxidant ability.