Clinical trial of the neuroprotectant clomethiazole in coronary artery bypass graft surgery: a randomized controlled trial.

Kong, Robert S; Butterworth, John; Aveling, Wynne; Stump, David A; Harrison, Michael J G; Hammon, John; Stygall, Jan; Rorie, Kashemi D; Newman, Stanton P

Kong, Robert S; Butterworth, John; Aveling, Wynne; Stump, David A; Harrison, Michael J G; Hammon, John; Stygall, Jan; Rorie, Kashemi D; Newman, Stanton P.

Affiliation

Kong RS; Health Psychology Unit, Academic Department of Psychiatry & Behavioural Sciences, Reta Lila Weston Institute of Neurological Studies, Royal Free and University College London Medical School, United Kingdom.

Anesthesiology ; 97(3): 585-91, 2002 Sep.

Article in En | MEDLINE | ID: mdl-12218524

Subject(s)

Chlormethiazole/therapeutic use; Coronary Artery Bypass; Neuroprotective Agents/therapeutic use; Postoperative Complications/drug therapy; Postoperative Complications/psychology; Affect/drug effects; Aged; Chlormethiazole/administration & dosage; Chlormethiazole/blood; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Infusions, Intravenous; Intracranial Embolism and Thrombosis/prevention & control; Male; Middle Aged; Neuroprotective Agents/administration & dosage; Neuroprotective Agents/blood; Neuropsychological Tests; Prospective Studies; Treatment Outcome

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Collection: 01-internacional Database: MEDLINE Main subject: Postoperative Complications / Chlormethiazole / Coronary Artery Bypass / Neuroprotective Agents Type of study: Clinical_trials / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Aged / Female / Humans / Male / Middle aged Language: En Journal: Anesthesiology Year: 2002 Document type: Article Affiliation country: United kingdom Country of publication: United States

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