Regulation of insulin action and pancreatic beta-cell function by mutated alleles of the gene encoding forkhead transcription factor Foxo1.

Nakae, Jun; Biggs, William H; Kitamura, Tadahiro; Cavenee, Webster K; Wright, Christopher V E; Arden, Karen C; Accili, Domenico

Nakae, Jun; Biggs, William H; Kitamura, Tadahiro; Cavenee, Webster K; Wright, Christopher V E; Arden, Karen C; Accili, Domenico.

Affiliation

Nakae J; Naomi Berrie Diabetes Center, Berrie Research Pavilion, 1150 St. Nicholas Avenue, Department of Medicine, College of Physicians & Surgeons of Columbia University, New York, New York 10032, USA.

Nat Genet ; 32(2): 245-53, 2002 Oct.

Article in En | MEDLINE | ID: mdl-12219087

Subject(s)

Insulin/physiology; Islets of Langerhans/physiology; Transcription Factors/genetics; Animals; Blotting, Northern; Diabetes Mellitus, Experimental/genetics; Diabetes Mellitus, Experimental/metabolism; Diabetes Mellitus, Type 2/etiology; Diabetes Mellitus, Type 2/genetics; Diabetes Mellitus, Type 2/metabolism; Forkhead Box Protein O1; Forkhead Transcription Factors; Immunohistochemistry; Insulin Resistance/genetics; Liver/metabolism; Mice; Mice, Transgenic; Mutation; Organ Specificity; Receptor, Insulin/genetics; Transcription Factors/physiology

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Collection: 01-internacional Database: MEDLINE Main subject: Transcription Factors / Islets of Langerhans / Insulin Type of study: Etiology_studies Limits: Animals Language: En Journal: Nat Genet Journal subject: GENETICA MEDICA Year: 2002 Document type: Article Affiliation country: United States

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