Between-eye asymmetry in keratoconus.
Cornea
; 21(7): 671-9, 2002 Oct.
Article
in En
| MEDLINE
| ID: mdl-12352084
ABSTRACT
PURPOSE:
To report baseline differences between eyes on key variables in the Collaborative Longitudinal Evaluation of Keratoconus (CLEK) Study cohort compared with a retrospectively assembled group of myopic contact lens wearers without ocular disease.METHODS:
A total of 1,079 keratoconus patients who had not undergone a penetrating keratoplasty in either eye before their baseline visit were enrolled and examined at baseline. Records from 330 contact lens-wearing myopes were reviewed. Corneal curvature (keratometry), visual acuity, refractive error (manifest refraction), and corneal scarring were measured.RESULTS:
The mean differences between keratoconic eyes are as follows (better eye-worse eye for each variable, separately). Flat keratometry -3.59 +/-4.46 D and steep keratometry -4.35 +/-4.41 D; high-contrast best-corrected visual acuity 7.30 +/-6.83 letters; low-contrast best-corrected visual acuity 8.53 +/-7.51 letters; high-contrast entrance visual acuity 9.03 +/-8.40 letters; low-contrast entrance visual acuity 9.43 +/-7.88 letters; spherical equivalent refractive error 3.15 +/-3.84 D; and refractive cylinder power 1.55 +/-1.42 D. Twenty-one percent of the keratoconus patients had corneal scarring in only one eye. There is an association between patient-reported unilateral eye rubbing and greater asymmetry in corneal curvature, and between a history of unilateral eye trauma and greater asymmetry in corneal curvature and refractive error, with the rubbed/traumatized eye being the steeper eye most of the time.CONCLUSIONS:
Keratoconus is asymmetric in the CLEK Study sample.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Cornea
/
Keratoconus
Type of study:
Etiology_studies
/
Incidence_studies
/
Observational_studies
/
Risk_factors_studies
Limits:
Adult
/
Humans
/
Middle aged
Language:
En
Journal:
Cornea
Year:
2002
Document type:
Article
Affiliation country:
United States