Drug specific resistance to oxaliplatin is associated with apoptosis defect in a cellular model of colon carcinoma.

Gourdier, Isabelle; Del Rio, Maguy; Crabbé, Laure; Candeil, Laurent; Copois, Virginie; Ychou, Marc; Auffray, Charles; Martineau, Pierre; Mechti, Nadir; Pommier, Yves; Pau, Bernard

Gourdier, Isabelle; Del Rio, Maguy; Crabbé, Laure; Candeil, Laurent; Copois, Virginie; Ychou, Marc; Auffray, Charles; Martineau, Pierre; Mechti, Nadir; Pommier, Yves; Pau, Bernard.

Affiliation

Gourdier I; CNRS UMR 5094, Faculté de Pharmacie, 15 avenue Charles Flahaut, P.O. Box 14491, 34093 Montpellier, France.

FEBS Lett ; 529(2-3): 232-6, 2002 Oct 09.

Article in En | MEDLINE | ID: mdl-12372606

Subject(s)

Antineoplastic Agents/pharmacology; Apoptosis; Colonic Neoplasms/pathology; Models, Biological; Organoplatinum Compounds/pharmacology; Arsenic Trioxide; Arsenicals/pharmacology; Base Sequence; Blotting, Western; Caspase 3; Caspases/genetics; DNA Primers; Drug Resistance, Neoplasm; Flow Cytometry; Humans; Indazoles/pharmacology; Oxaliplatin; Oxides/pharmacology; Proto-Oncogene Proteins c-bcl-2/genetics

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Collection: 01-internacional Database: MEDLINE Main subject: Organoplatinum Compounds / Apoptosis / Colonic Neoplasms / Models, Biological / Antineoplastic Agents Type of study: Prognostic_studies / Risk_factors_studies Limits: Humans Language: En Journal: FEBS Lett Year: 2002 Document type: Article Affiliation country: France Country of publication: United kingdom

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