Identification of a new HLA-A null allele, A*2436 N.

Li, J; den Hollander, N; van Oosterwijk, A; Ng, C-M; Singal, D P

Li, J; den Hollander, N; van Oosterwijk, A; Ng, C-M; Singal, D P.

Affiliation

Li J; Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Ontario, Canada.

Tissue Antigens ; 60(2): 184-5, 2002 Aug.

Article in En | MEDLINE | ID: mdl-12392513

ABSTRACT

We describe a new HLA-A null allele in a donor. This null allele resulted from the deletion of two nucleotides in exon 2, which effects a frameshift as well as a premature stop codon. This new null allele has been officially named HLA-A*2436 N.

Subject(s)

Alleles; HLA-A Antigens/genetics; Base Sequence; Codon, Nonsense; HLA-A Antigens/classification; Humans; Molecular Sequence Data; Point Mutation

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Collection: 01-internacional Database: MEDLINE Main subject: HLA-A Antigens / Alleles Type of study: Diagnostic_studies Limits: Humans Language: En Journal: Tissue Antigens Year: 2002 Document type: Article Affiliation country: Canada Country of publication: United kingdom

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