The antimicrobial activity of Aspergillus fumigatus is enhanced by a pool of bacteria.
Microbiol Res
; 157(3): 207-11, 2002.
Article
in En
| MEDLINE
| ID: mdl-12398291
ABSTRACT
In a screening program for new antibiotic producers, a strain of Aspergillus fumigatus was isolated from Brazilian soil samples. A pool of autoclaved bacteria was added to part of the fungus culture on the second day of fermentation to increase antibiotic production. The chloroform extract from the culture broth to which the pool of autoclaved bacteria was added showed an increase of 55%, 63% and more than 100% in activity against Staphylococcus aureus, Candida albicans and Micrococcus luteus, respectively. Also, the HPLC chromatographic profiles of the chloroform extracts from both culture conditions were different. Two active compounds were isolated from the broth of the culture grown in the presence of pooled bacteria and were identified as 3,4-dimethoxyphenol and 1,3,5-trimethoxybenzene.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Aspergillus fumigatus
/
Anti-Bacterial Agents
Country/Region as subject:
America do sul
/
Brasil
Language:
En
Journal:
Microbiol Res
Journal subject:
MICROBIOLOGIA
/
SAUDE AMBIENTAL
Year:
2002
Document type:
Article
Affiliation country:
Brazil