Bax is crucial for IFN-gamma-induced resolution of allergen-induced mucus cell metaplasia.

Tesfaigzi, Yohannes; Fischer, Mark J; Daheshia, Massoud; Green, Francis H Y; De Sanctis, George T; Wilder, Julie A

Tesfaigzi, Yohannes; Fischer, Mark J; Daheshia, Massoud; Green, Francis H Y; De Sanctis, George T; Wilder, Julie A.

Affiliation

Tesfaigzi Y; Lovelace Respiratory Research Institute, 2425 Ridgecrest Drive SE, Albuquerque, NM 87108, USA. ytesfaig@lrri.org

J Immunol ; 169(10): 5919-25, 2002 Nov 15.

Article in En | MEDLINE | ID: mdl-12421976

Subject(s)

Allergens/administration & dosage; Interferon-gamma/therapeutic use; Lung/immunology; Lung/pathology; Mucus/cytology; Mucus/immunology; Proto-Oncogene Proteins c-bcl-2/physiology; Proto-Oncogene Proteins/physiology; Animals; Bronchi/immunology; Bronchi/metabolism; Cell Count; Culture Techniques; Dissection; Eosinophilia/immunology; Inflammation/genetics; Inflammation/immunology; Inflammation/prevention & control; Lung/metabolism; Male; Metaplasia/genetics; Metaplasia/immunology; Metaplasia/pathology; Metaplasia/prevention & control; Mice; Mice, Inbred C57BL; Mice, Knockout; Mucus/metabolism; Ovalbumin/administration & dosage; P-Selectin/genetics; Proto-Oncogene Proteins/biosynthesis; Respiratory Hypersensitivity/genetics; Respiratory Hypersensitivity/immunology; Respiratory Hypersensitivity/pathology; Respiratory Hypersensitivity/prevention & control; bcl-2-Associated X Protein

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Collection: 01-internacional Database: MEDLINE Main subject: Allergens / Proto-Oncogene Proteins / Interferon-gamma / Proto-Oncogene Proteins c-bcl-2 / Lung / Mucus Limits: Animals Language: En Journal: J Immunol Year: 2002 Document type: Article Affiliation country: United States

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