MMP-9 correlates with electrophysiologic abnormalities in Guillain-Barré syndrome.
Neurology
; 59(10): 1649-51, 2002 Nov 26.
Article
in En
| MEDLINE
| ID: mdl-12451218
ABSTRACT
To investigate the role of MMP-9 in Guillain-Barré syndrome, the authors correlated electrophysiologic abnormalities and MMP-9 plasma levels in a series of 21 patients. MMP-9 plasma levels were higher in the demyelinating group than in the nondemyelinating group, and in patients with high CSF protein level. Increase of MMP-9 circulating levels correlated with the increase of F waves latencies, reduction of CMAP amplitude, and decrease of nerve conduction velocities. Circulating MMP-9 may contribute to the peripheral nerve dysfunction of demyelinating Guillain-Barré syndrome.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Guillain-Barre Syndrome
/
Matrix Metalloproteinase 9
Limits:
Adult
/
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Language:
En
Journal:
Neurology
Year:
2002
Document type:
Article
Affiliation country:
France