A cleavable adapter to reduce nonspecific cytotoxicity of recombinant immunotoxins.

Heisler, Iring; Keller, Jutta; Tauber, Rudolf; Sutherland, Mark; Fuchs, Hendrik

Heisler, Iring; Keller, Jutta; Tauber, Rudolf; Sutherland, Mark; Fuchs, Hendrik.

Affiliation

Heisler I; Institut für Klinische Chemie und Pathobiochemie, Universitätsklinikum Benjamin Franklin, Freie Universität Berlin, Berlin, Germany.

Int J Cancer ; 103(2): 277-82, 2003 Jan 10.

Article in En | MEDLINE | ID: mdl-12455044

Subject(s)

Immunotoxins/toxicity; N-Glycosyl Hydrolases/toxicity; Plant Proteins/toxicity; Tumor Cells, Cultured/drug effects; Adenine/metabolism; Cell Division/drug effects; DNA Primers/chemistry; Epidermal Growth Factor/toxicity; ErbB Receptors/metabolism; Glycoside Hydrolases/metabolism; Half-Life; Hepatitis B Surface Antigens/genetics; Hepatitis B Surface Antigens/metabolism; Humans; In Vitro Techniques; Polymerase Chain Reaction; Recombinant Proteins/metabolism; Recombinant Proteins/toxicity; Ribosome Inactivating Proteins, Type 1; Saporins; Tumor Cells, Cultured/metabolism

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Collection: 01-internacional Database: MEDLINE Main subject: Plant Proteins / Tumor Cells, Cultured / Immunotoxins / N-Glycosyl Hydrolases Limits: Humans Language: En Journal: Int J Cancer Year: 2003 Document type: Article Affiliation country: Germany

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