Evaluation of in vitro and in vivo activity of benzindazole-4,9-quinones against Cryptosporidium parvum.

Kayser, Oliver; Waters, W Ray; Woods, Keith M; Upton, Steve J; Keithly, Janet S; Laatsch, Hartmut; Kiderlen, Albrecht F

Kayser, Oliver; Waters, W Ray; Woods, Keith M; Upton, Steve J; Keithly, Janet S; Laatsch, Hartmut; Kiderlen, Albrecht F.

Affiliation

Kayser O; Freie Universität Berlin, Institut für Pharmazie, Pharmazeutische Technologie, Biopharmazie und Biotechnologie, Kelchstrasse 31, 12169 Berlin. kayser@zedat.fu-berlin.de

J Antimicrob Chemother ; 50(6): 975-80, 2002 Dec.

Article in En | MEDLINE | ID: mdl-12461020

Subject(s)

Cryptosporidiosis/drug therapy; Cryptosporidium parvum/drug effects; Cryptosporidium parvum/growth & development; Quinones/pharmacology; Quinones/therapeutic use; Animals; Cattle; Cecal Diseases/drug therapy; Cecal Diseases/microbiology; Cell Line; Cryptosporidiosis/microbiology; Cryptosporidium parvum/isolation & purification; Disease Models, Animal; Drug Evaluation, Preclinical/methods; Epithelial Cells/drug effects; Genes, T-Cell Receptor alpha/drug effects; Genes, T-Cell Receptor alpha/physiology; Humans; Ileal Diseases/drug therapy; Ileal Diseases/microbiology; Mice; Quinones/chemistry; Quinones/isolation & purification

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Collection: 01-internacional Database: MEDLINE Main subject: Quinones / Cryptosporidium parvum / Cryptosporidiosis Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: J Antimicrob Chemother Year: 2002 Document type: Article Country of publication: United kingdom

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