Stability of individual differences in cellular immune responses to two different laboratory tasks.
Psychophysiology
; 39(6): 865-8, 2002 Nov.
Article
in En
| MEDLINE
| ID: mdl-12462514
ABSTRACT
To explore the stability of immune reactivity across laboratory tasks, we correlated enumerative and functional lymphocyte responses to a speech task and a mental arithmetic task, delivered on the same occasion of testing in 31 healthy undergraduates. Both tasks were associated with an increase in peripheral CD8+ and CD56+ cell populations, and a decrease in proliferative response to phytohemagglutinin (PHA) and ratio of CD4CD8 cells. Intertask correlations were significant for the magnitude of change in proliferative responses at two different concentrations of PHA, r = 0.76, p < .0001 and r = 0.46, p < .05, and in numbers of circulating CD56+ cells, r = 0.46, p < .005. Concomitant heart rate and systolic blood pressure responses also correlated significantly over the two experimental tasks (heart rate r = 0.52 and systolic blood pressure r = 0.58. ps < .0005). These data provide initial evidence that interindividual variability of some cellular immune responses is moderately reproducible across different stimulus conditions, providing further evidence that it may denote a stable individual difference.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Arousal
/
Problem Solving
/
Speech
/
Killer Cells, Natural
/
Lymphocyte Activation
/
CD8-Positive T-Lymphocytes
/
Individuality
Limits:
Adolescent
/
Adult
/
Female
/
Humans
/
Male
Language:
En
Journal:
Psychophysiology
Year:
2002
Document type:
Article
Affiliation country:
United States