[The changes of IL-1 and NO levels in the testes of rats with experimental varicocele].
Zhonghua Nan Ke Xue
; 8(2): 125-6, 2002.
Article
in Zh
| MEDLINE
| ID: mdl-12479028
ABSTRACT
OBJECTIVES:
To evaluate the effects of varicocele (VC) on IL-1 and NO levels in testes of rats with VC.METHODS:
Male adult Wistar rats were divided into two groups randomly, VC group (n = 30) and pseudo-operation group (n = 20), and the levels of IL-1 and NO in the testes were determined and compared.RESULTS:
The levels of IL-1 and No of left tests in VC group were higher than those in pseudo-operation group, respectively(P < 0.01). While the levels of IL-1 and NO of right testes between two groups were not significantly different (P > 0.05). More over, the level of IL-1 correlated significantly with that of NO(r = 0.572, P < 0.01).CONCLUSIONS:
The results revealed that the changes of IL-1 and NO levels in the testes of rats with VC might be the reason which caused testes damage, disturbance of spermatogenesis and even infertility.
Search on Google
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Testis
/
Varicocele
/
Interleukin-1
/
Nitric Oxide
Type of study:
Prognostic_studies
Limits:
Animals
Language:
Zh
Journal:
Zhonghua Nan Ke Xue
Journal subject:
MEDICINA REPRODUTIVA
Year:
2002
Document type:
Article
Affiliation country:
China
Publication country:
CHINA
/
CN
/
REPUBLIC OF CHINA