Assessment of the effect of phosphorylated metabolites of anti-human immunodeficiency virus and anti-hepatitis B virus pyrimidine analogs on the behavior of human deoxycytidylate deaminase.

Liou, Jieh-Yuan; Krishnan, Preethi; Hsieh, Cheng-Chih; Dutschman, Ginger E; Cheng, Yung-Chi

Liou, Jieh-Yuan; Krishnan, Preethi; Hsieh, Cheng-Chih; Dutschman, Ginger E; Cheng, Yung-Chi.

Affiliation

Liou JY; Department of Pharmacology, Yale University School of Medicine, New Haven, Connecticut 06520, USA.

Mol Pharmacol ; 63(1): 105-10, 2003 Jan.

Article in En | MEDLINE | ID: mdl-12488542

Subject(s)

Antiviral Agents/pharmacology; DCMP Deaminase/metabolism; Antiviral Agents/metabolism; DCMP Deaminase/drug effects; Deamination; Deoxycytidine Monophosphate/analogs & derivatives; Deoxycytidine Monophosphate/metabolism; HIV/drug effects; Hepatitis B virus/drug effects; Humans; Pyrimidines/metabolism; Substrate Specificity; Tumor Cells, Cultured

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Collection: 01-internacional Database: MEDLINE Main subject: Antiviral Agents / DCMP Deaminase Limits: Humans Language: En Journal: Mol Pharmacol Year: 2003 Document type: Article Affiliation country: United States Country of publication: United States

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