Legionnaires' disease at a Dutch flower show: prognostic factors and impact of therapy.
Emerg Infect Dis
; 8(12): 1448-54, 2002 Dec.
Article
in En
| MEDLINE
| ID: mdl-12498662
ABSTRACT
After a large outbreak of Legionnaires' disease in the Netherlands, we determined risk factors for intensive care unit (ICU) admission and death and the impact of adequate therapy on ICU-free survival among 141 hospitalized patients. Overall mortality rate was 13%, and ICU mortality rate was 36%. Smoking, temperature >38.5 degrees C, and bilateral infiltrates shown on chest x-ray were independent risk factors for ICU admission or death (all p<0.05). Starting adequate therapy within 24 hours after admission resulted in a higher ICU-free survival rate compared to therapy initiation after 24 hours 78% versus 54%, respectively (p=0.005). However, delay in providing therapy to patients with urinary antigen tests with negative results did not influence outcome. These data suggest that by using the urinary antigen test on admission a more tailored approach to patients with community-acquired pneumonia may be applied.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Legionnaires' Disease
/
Disease Outbreaks
/
Anti-Bacterial Agents
Type of study:
Diagnostic_studies
/
Etiology_studies
/
Prognostic_studies
/
Risk_factors_studies
Limits:
Aged
/
Female
/
Humans
/
Male
Country/Region as subject:
Europa
Language:
En
Journal:
Emerg Infect Dis
Journal subject:
DOENCAS TRANSMISSIVEIS
Year:
2002
Document type:
Article
Affiliation country:
Netherlands