Physiological and molecular effects of Apo2L/TRAIL and cisplatin in ovarian carcinoma cell lines.

Siervo-Sassi, R R; Marrangoni, A M; Feng, X; Naoumova, N; Winans, M; Edwards, R P; Lokshin, A

Siervo-Sassi, R R; Marrangoni, A M; Feng, X; Naoumova, N; Winans, M; Edwards, R P; Lokshin, A.

Affiliation

Siervo-Sassi RR; Department of Ob/Gyn Reproductive Sciences, Magee Women's Research Institute, University of Pittsburgh, 204 Craft Avenue, Pittsburgh, PA 15213, USA.

Cancer Lett ; 190(1): 61-72, 2003 Feb 10.

Article in En | MEDLINE | ID: mdl-12536078

Subject(s)

Antineoplastic Agents/pharmacology; Cisplatin/pharmacology; Membrane Glycoproteins/pharmacology; Ovarian Neoplasms/drug therapy; Tumor Necrosis Factor-alpha/pharmacology; Apoptosis; Apoptosis Regulatory Proteins; Blotting, Western; Caspases/metabolism; Cell Death; Cell Division; Cell Line; DNA, Complementary/metabolism; Down-Regulation; Female; Flow Cytometry; Humans; Mitochondria/metabolism; Oligonucleotide Array Sequence Analysis; Proteins/metabolism; Proto-Oncogene Proteins c-bcl-2/metabolism; TNF Receptor-Associated Factor 5; TNF Receptor-Associated Factor 6; TNF-Related Apoptosis-Inducing Ligand; Time Factors; Tumor Cells, Cultured; Up-Regulation; bcl-X Protein

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Collection: 01-internacional Database: MEDLINE Main subject: Ovarian Neoplasms / Membrane Glycoproteins / Tumor Necrosis Factor-alpha / Cisplatin / Antineoplastic Agents Limits: Female / Humans Language: En Journal: Cancer Lett Year: 2003 Document type: Article Affiliation country: United States Country of publication: Ireland

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