Global expression profiling of fibroblast responses to transforming growth factor-beta1 reveals the induction of inhibitor of differentiation-1 and provides evidence of smooth muscle cell phenotypic switching.

Chambers, Rachel C; Leoni, Patricia; Kaminski, Naftali; Laurent, Geoffrey J; Heller, Renu A

Chambers, Rachel C; Leoni, Patricia; Kaminski, Naftali; Laurent, Geoffrey J; Heller, Renu A.

Affiliation

Chambers RC; Centre for Cardiopulmonary Biochemistry and Respiratory Medicine, Royal Free and University College Medical School, University College London, Rayne Institute, London, United Kingdom. r.chambers@ucl.ac.uk

Am J Pathol ; 162(2): 533-46, 2003 Feb.

Article in En | MEDLINE | ID: mdl-12547711

Subject(s)

Fibroblasts/physiology; Gene Expression Profiling; Muscle, Smooth/physiology; Neoplasm Proteins/genetics; Repressor Proteins; Transcription, Genetic; Transforming Growth Factor beta/pharmacology; Cell Division; Cell Line; Cell Survival; Fetus; Fibroblasts/drug effects; Helix-Loop-Helix Motifs; Humans; Immunohistochemistry; Inhibitor of Differentiation Protein 1; Inhibitor of Differentiation Proteins; Lung; Muscle, Smooth/cytology; Phenotype; RNA, Messenger/genetics; Transcription Factors/genetics; Transforming Growth Factor beta1

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Repressor Proteins / Transcription, Genetic / Transforming Growth Factor beta / Gene Expression Profiling / Fibroblasts / Muscle, Smooth / Neoplasm Proteins Limits: Humans Language: En Journal: Am J Pathol Year: 2003 Document type: Article Affiliation country: United kingdom Country of publication: United States

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