Anti-Nogo-A antibody infusion 24 hours after experimental stroke improved behavioral outcome and corticospinal plasticity in normotensive and spontaneously hypertensive rats.

Wiessner, Christoph; Bareyre, Florence M; Allegrini, Peter R; Mir, Anis K; Frentzel, Stefan; Zurini, Mauro; Schnell, Lisa; Oertle, Thomas; Schwab, Martin E

Wiessner, Christoph; Bareyre, Florence M; Allegrini, Peter R; Mir, Anis K; Frentzel, Stefan; Zurini, Mauro; Schnell, Lisa; Oertle, Thomas; Schwab, Martin E.

Affiliation

Wiessner C; Nervous Systeme Research, Novartis Parma AG, Basel, Switzerland. christoph.wiessner@pharma.novartis.com

J Cereb Blood Flow Metab ; 23(2): 154-65, 2003 Feb.

Article in En | MEDLINE | ID: mdl-12571447

Subject(s)

Antibodies, Monoclonal/administration & dosage; Behavior, Animal/drug effects; Hypertension/complications; Myelin Proteins/immunology; Stroke/physiopathology; Stroke/psychology; Animals; Antibodies, Monoclonal/pharmacokinetics; Arterial Occlusive Diseases/complications; Brain/metabolism; Cerebral Arteries; Cerebral Infarction/etiology; Cerebral Infarction/pathology; Cerebral Infarction/psychology; Drug Administration Schedule; Injections, Intraventricular; Male; Neuronal Plasticity/drug effects; Nogo Proteins; Pyramidal Tracts/pathology; Pyramidal Tracts/physiopathology; Rats; Rats, Inbred F344; Rats, Inbred SHR; Stroke/etiology; Tissue Distribution

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Collection: 01-internacional Database: MEDLINE Main subject: Behavior, Animal / Stroke / Hypertension / Antibodies, Monoclonal / Myelin Proteins Type of study: Etiology_studies Limits: Animals Language: En Journal: J Cereb Blood Flow Metab Year: 2003 Document type: Article Affiliation country: Switzerland Country of publication: United States

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