Intrathecal administration of morphine, but not small dose, induced spastic paraparesis after a noninjurious interval of aortic occlusion in rats.

Cousins, Michael J; Kakinohana, Manabu; Fuchigami, Tatsuya; Nakamura, Seiya; Sasara, Takeshi; Kawabata, Tetsuya; Sugahara, Kazuhiro

Cousins, Michael J; Kakinohana, Manabu; Fuchigami, Tatsuya; Nakamura, Seiya; Sasara, Takeshi; Kawabata, Tetsuya; Sugahara, Kazuhiro.

Affiliation

Cousins MJ; Department of Anesthesiology, Faculty of Medicine, University of the Ryukyus, Okinawa, Japan.

Anesth Analg ; 96(3): 769-775, 2003 Mar.

Article in En | MEDLINE | ID: mdl-12598261

Subject(s)

Analgesics, Opioid/pharmacology; Morphine/pharmacology; Paraparesis, Spastic/chemically induced; Analgesics, Opioid/administration & dosage; Animals; Aorta/physiology; Body Temperature/drug effects; Dose-Response Relationship, Drug; Injections, Spinal; Male; Morphine/administration & dosage; Motor Neurons/physiology; Paraparesis, Spastic/physiopathology; Rats; Rats, Sprague-Dawley; Reperfusion Injury/pathology; Reperfusion Injury/physiopathology; Spinal Cord/pathology; Spinal Cord Ischemia/pathology; Spinal Cord Ischemia/physiopathology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Paraparesis, Spastic / Analgesics, Opioid / Morphine Limits: Animals Language: En Journal: Anesth Analg Year: 2003 Document type: Article Affiliation country: Japan Country of publication: United States

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