Alteration of Escherichia coli topoisomerase IV to novobiocin resistance.

Hardy, Christine D; Cozzarelli, Nicholas R

Hardy, Christine D; Cozzarelli, Nicholas R.

Affiliation

Hardy CD; Department of Molecular and Cell Biology, University of California, Berkeley 94720-3204, USA.

Antimicrob Agents Chemother ; 47(3): 941-7, 2003 Mar.

Article in En | MEDLINE | ID: mdl-12604525

Subject(s)

Anti-Bacterial Agents/pharmacology; DNA Topoisomerase IV/genetics; Escherichia coli/enzymology; Escherichia coli/genetics; Mutation/genetics; Novobiocin/pharmacology; Adenosine Triphosphate/metabolism; Amino Acid Sequence; Codon; Coumarins/pharmacology; DNA Gyrase/genetics; DNA Gyrase/metabolism; DNA, Superhelical/chemistry; DNA, Superhelical/drug effects; Drug Resistance, Bacterial; Models, Molecular; Molecular Sequence Data

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Novobiocin / DNA Topoisomerase IV / Escherichia coli / Anti-Bacterial Agents / Mutation Language: En Journal: Antimicrob Agents Chemother Year: 2003 Document type: Article Affiliation country: United States Country of publication: United States

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