N-(4-hydroxyphenyl)retinamide inhibits retinoblastoma growth through reactive oxygen species-mediated cell death.

Tosetti, Francesca; Venè, Roberta; Arena, Giuseppe; Morini, Monica; Minghelli, Simona; Noonan, Douglas M; Albini, Adriana

Tosetti, Francesca; Venè, Roberta; Arena, Giuseppe; Morini, Monica; Minghelli, Simona; Noonan, Douglas M; Albini, Adriana.

Affiliation

Tosetti F; Molecular Oncology Laboratory, Genova, Italy.

Mol Pharmacol ; 63(3): 565-73, 2003 Mar.

Article in En | MEDLINE | ID: mdl-12606763

Subject(s)

Antineoplastic Agents/pharmacology; Cell Death; Fenretinide/pharmacology; Reactive Oxygen Species/metabolism; Retinoblastoma/pathology; Animals; Antineoplastic Agents/therapeutic use; Cell Survival/drug effects; Disease Models, Animal; Fenretinide/therapeutic use; Humans; Mice; Mice, Nude; Neoplasm Transplantation; Neoplasms, Experimental/drug therapy; Neovascularization, Pathologic/drug therapy; Retinoblastoma/drug therapy; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

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Collection: 01-internacional Database: MEDLINE Main subject: Retinoblastoma / Cell Death / Reactive Oxygen Species / Fenretinide / Antineoplastic Agents Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Mol Pharmacol Year: 2003 Document type: Article Affiliation country: Italy Country of publication: United States

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