Degree of tumour vascularity correlates with drug accumulation and tumour response upon TNF-alpha-based isolated hepatic perfusion.

van Etten, B; de Vries, M R; van IJken, M G A; Lans, T E; Guetens, G; Ambagtsheer, G; van Tiel, S T; de Boeck, G; de Bruijn, E A; Eggermont, A M M; ten Hagen, T L M

van Etten, B; de Vries, M R; van IJken, M G A; Lans, T E; Guetens, G; Ambagtsheer, G; van Tiel, S T; de Boeck, G; de Bruijn, E A; Eggermont, A M M; ten Hagen, T L M.

Affiliation

van Etten B; Department of Surgical Oncology, University Hospital Rotterdam-Daniel den Hoed Cancer Center, Rotterdam, The Netherlands.

Br J Cancer ; 88(2): 314-9, 2003 Jan 27.

Article in En | MEDLINE | ID: mdl-12610519

Subject(s)

Antineoplastic Agents, Alkylating/pharmacokinetics; Antineoplastic Agents/administration & dosage; Liver Neoplasms, Experimental/blood supply; Liver Neoplasms, Experimental/metabolism; Melphalan/pharmacokinetics; Tumor Necrosis Factor-alpha/administration & dosage; Animals; Cell Division/drug effects; Chemotherapy, Cancer, Regional Perfusion/methods; Colonic Neoplasms/blood supply; Colonic Neoplasms/metabolism; Disease Models, Animal; Immunoenzyme Techniques; In Vitro Techniques; Liver Neoplasms, Experimental/secondary; Male; Microcirculation; Osteosarcoma/blood supply; Osteosarcoma/metabolism; Rats; Rats, Inbred BN; Sarcoma/blood supply; Sarcoma/metabolism; Tissue Distribution

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Tumor Necrosis Factor-alpha / Antineoplastic Agents, Alkylating / Liver Neoplasms, Experimental / Melphalan / Antineoplastic Agents Type of study: Prognostic_studies Limits: Animals Language: En Journal: Br J Cancer Year: 2003 Document type: Article Affiliation country: Netherlands Country of publication: United kingdom

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