Perioperative risk factors for mortality in patients with acute type A aortic dissection.
Ann Thorac Surg
; 74(6): 2034-9; discussion 2039, 2002 Dec.
Article
in En
| MEDLINE
| ID: mdl-12643392
ABSTRACT
BACKGROUND:
This study was undertaken to identify the perioperative risk factors for death in patients with acute type A aortic dissection (AADA).METHODS:
Between 1993 and 2001, 108 consecutive patients (86 men; mean age, 53 years) underwent emergent operations for AADA. All patients but 2 underwent replacement of the ascending aorta with an open distal anastomosis during a period of hypothermic circulatory arrest. In addition, 22 patients had hemiarch and 5 had total arch replacement. Aortic root was replaced in 20 and repaired with gelatin-resorcinol-formaldehyde glue in 39 patients; aortic valve was separately replaced in 3, resuspended in 24, and remained untouched in 22 patients.RESULTS:
Overall in-hospital mortality was 25%. Mortality rate was significantly higher in patients with preoperative dissection complications than in those without (21/36 [58%] vs 6/72 [8%], p < 0.001). In multivariate analysis, predictors of mortality were presence of rupture, renal failure, and intestinal malperfusion, duration of cardiopulmonary bypass > or = 200 minutes, blood loss > or = 500 mL, and transfusion of blood > or = 4 units. Location of the intimal tear, extent of the replacement, type of the aortic root repair, and duration of hypothermic circulatory arrest did not emerge as predictors of mortality.CONCLUSIONS:
Major determinants of surgical mortality in patients with AADA are preoperative complications. Earlier diagnosis remains essential to improve the survival rate.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Aortic Aneurysm, Thoracic
/
Aortic Dissection
Type of study:
Etiology_studies
/
Prognostic_studies
/
Risk_factors_studies
Limits:
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Language:
En
Journal:
Ann Thorac Surg
Year:
2002
Document type:
Article
Affiliation country:
Turkey