Event-related potentials P300 in type 2 diabetes mellitus.
Di Yi Jun Yi Da Xue Xue Bao
; 23(3): 257-9, 2003 Mar.
Article
in En
| MEDLINE
| ID: mdl-12651246
ABSTRACT
OBJECTIVE:
To investigate event-related potentials (ERP) P(300) in patients with type 2 diabetes mellitus (DM) for early detection of the abnormalities in cognitive function and studying the related factors.METHODS:
With the assistance of Nicolet Vinking IV equipment, ERP (P(300)) were tested in 30 type 2 diabetic patients and 30 healthy subjects matched for age, gender, and education background, and the the results were analyzed statistically. The relationships of each ERP parameter with glucose hemoglobin (GHb) and blood lipid levels and renal function were analyzed.RESULTS:
No significant difference was found in P(300) latencies in the control group irrespective of the gender and education (P > 0.05), while the latencies were significantly prolonged (P < 0.01) and the amplitudes decreased (P < 0.05) in diabetic patients. It was found that P(300) correlated with glucose hemoglobin (GHb) and blood lipid levels (P < 0.05).CONCLUSION:
ERP test is useful for early detection of cognition dysfunction in DM cases, helping to timely identify diabetic patients with potential dementia.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Cognition Disorders
/
Event-Related Potentials, P300
/
Diabetes Mellitus, Type 2
Type of study:
Prognostic_studies
/
Screening_studies
Limits:
Adult
/
Aged
/
Aged80
/
Female
/
Humans
/
Male
/
Middle aged
Language:
En
Journal:
Di Yi Jun Yi Da Xue Xue Bao
Journal subject:
MEDICINA
Year:
2003
Document type:
Article