Comparative studies on the microbiological vitamin B12 assay at two laboratories.
Appl Environ Microbiol
; 31(4): 459-64, 1976 Apr.
Article
in En
| MEDLINE
| ID: mdl-1267444
ABSTRACT
The turbidimetric methods in routine use at two laboratories for the microbiological assay of vitamin B12 have been compared. Attempts were made to standardize some major parts of the method, i.e., assay design, test strain (Lactobacillus leichmannii), test medium, and reference standard. The laboratories used different approaches to achieve efficient assay procedures. During a 6-year period four comparative experiments were carried out. In these experiments the vitamin B12 content of five different products was determined in a series of independent assays at each laboratory. A satisfactory degree of agreement (difference less than 5%) was found for four of these products.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Vitamin B 12
/
Biological Assay
Country/Region as subject:
Europa
Language:
En
Journal:
Appl Environ Microbiol
Year:
1976
Document type:
Article