Noncatalytic domain of uPA stimulates human extravillous trophoblast migration by using phospholipase C, phosphatidylinositol 3-kinase and mitogen-activated protein kinase.

Liu, Jessica; Chakraborty, Chandan; Graham, Charles H; Barbin, Youssef P; Dixon, S Jeffrey; Lala, Peeyush K

Liu, Jessica; Chakraborty, Chandan; Graham, Charles H; Barbin, Youssef P; Dixon, S Jeffrey; Lala, Peeyush K.

Affiliation

Liu J; Department of Anatomy and Cell Biology, Medical Sciences Building, Faculty of Medicine and Dentistry, University of Western Ontario, London, Ontario, Canada N6A 5C1.

Exp Cell Res ; 286(1): 138-51, 2003 May 15.

Article in En | MEDLINE | ID: mdl-12729802

Subject(s)

Cell Movement; Mitogen-Activated Protein Kinases/metabolism; Phosphatidylinositol 3-Kinases/metabolism; Plasminogen Activators/metabolism; Trophoblasts/physiology; Type C Phospholipases/metabolism; Urokinase-Type Plasminogen Activator/metabolism; Calcium/metabolism; Cell Line; Culture Media, Serum-Free; Enzyme Inhibitors/metabolism; Humans; Peptide Fragments/metabolism; Plasminogen Activators/chemistry; Protein Structure, Tertiary; Signal Transduction/physiology; Trophoblasts/cytology; Urokinase-Type Plasminogen Activator/chemistry

Search on Google

Add to My VHL

XML

PubMed Links

Collection: 01-internacional Database: MEDLINE Main subject: Type C Phospholipases / Trophoblasts / Plasminogen Activators / Urokinase-Type Plasminogen Activator / Cell Movement / Phosphatidylinositol 3-Kinases / Mitogen-Activated Protein Kinases Limits: Humans Language: En Journal: Exp Cell Res Year: 2003 Document type: Article Country of publication: United States

Search on Google

Add to My VHL

XML

PubMed Links