p16/cyclin-dependent kinase inhibitor 2A deficiency in human melanocyte senescence, apoptosis, and immortalization: possible implications for melanoma progression.

Sviderskaya, Elena V; Gray-Schopfer, Vanessa C; Hill, Simon P; Smit, Nico P; Evans-Whipp, Tracy J; Bond, Jane; Hill, Lucy; Bataille, Veronique; Peters, Gordon; Kipling, David; Wynford-Thomas, David; Bennett, Dorothy C

Sviderskaya, Elena V; Gray-Schopfer, Vanessa C; Hill, Simon P; Smit, Nico P; Evans-Whipp, Tracy J; Bond, Jane; Hill, Lucy; Bataille, Veronique; Peters, Gordon; Kipling, David; Wynford-Thomas, David; Bennett, Dorothy C.

Affiliation

Sviderskaya EV; Department of Basic Medical Sciences, St. George's Hospital Medical School, London, UK.

J Natl Cancer Inst ; 95(10): 723-32, 2003 May 21.

Article in En | MEDLINE | ID: mdl-12759390

Subject(s)

Cyclin-Dependent Kinase Inhibitor p16/deficiency; Cyclin-Dependent Kinase Inhibitor p16/metabolism; Melanocytes/metabolism; Melanoma/metabolism; Telomerase/metabolism; Apoptosis; Cell Line, Transformed; Cellular Senescence; Cyclin-Dependent Kinase Inhibitor p21; Cyclins/metabolism; DNA-Binding Proteins; Disease Progression; Gene Expression Regulation, Neoplastic; Humans; Immunoblotting; Karyotyping; Kinetics; Phenotype

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Collection: 01-internacional Database: MEDLINE Main subject: Telomerase / Cyclin-Dependent Kinase Inhibitor p16 / Melanocytes / Melanoma Limits: Humans Language: En Journal: J Natl Cancer Inst Year: 2003 Document type: Article Affiliation country: United kingdom Country of publication: United States

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