Nutrient regulation of epothilone biosynthesis in heterologous and native production strains.

Regentin, R; Frykman, S; Lau, J; Tsuruta, H; Licari, P

Regentin, R; Frykman, S; Lau, J; Tsuruta, H; Licari, P.

Affiliation

Regentin R; Department of Process Sciences, Kosan Biosciences, 3832 Bay Center Place, Hayward, CA 94545, USA. regentin@kosan.com

Appl Microbiol Biotechnol ; 61(5-6): 451-5, 2003 Jun.

Article in En | MEDLINE | ID: mdl-12764559

Subject(s)

Epothilones/biosynthesis; Antineoplastic Agents/metabolism; Biotechnology; Culture Media; Fermentation; Iron/metabolism; Iron/pharmacology; Myxococcales/drug effects; Myxococcales/growth & development; Myxococcales/metabolism; Myxococcus xanthus/drug effects; Myxococcus xanthus/growth & development; Myxococcus xanthus/metabolism; Phosphates/metabolism; Phosphates/pharmacology

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Collection: 01-internacional Database: MEDLINE Main subject: Epothilones Language: En Journal: Appl Microbiol Biotechnol Year: 2003 Document type: Article Affiliation country: United States Country of publication: Germany

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