N-succinimidyl 3-[211At]astato-4-guanidinomethylbenzoate: an acylation agent for labeling internalizing antibodies with alpha-particle emitting 211At.

Vaidyanathan, Ganesan; Affleck, Donna J; Bigner, Darell D; Zalutsky, Michael R

Vaidyanathan, Ganesan; Affleck, Donna J; Bigner, Darell D; Zalutsky, Michael R.

Affiliation

Vaidyanathan G; Department of Radiology, Duke University, Durham, North Carolina 27710, USA. ganesan.v@duke.edu.

Nucl Med Biol ; 30(4): 351-9, 2003 May.

Article in En | MEDLINE | ID: mdl-12767391

Subject(s)

Antibodies, Monoclonal/radiation effects; Astatine/pharmacology; Benzoates/chemical synthesis; ErbB Receptors/radiation effects; Guanidine/analogs & derivatives; Guanidine/chemical synthesis; Radiopharmaceuticals/chemical synthesis; Acylation/radiation effects; Animals; Benzoates/pharmacokinetics; Benzoates/pharmacology; Guanidine/pharmacokinetics; Guanidine/pharmacology; Mice; Radiopharmaceuticals/pharmacokinetics; Radiopharmaceuticals/pharmacology; Tissue Distribution

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Collection: 01-internacional Database: MEDLINE Main subject: Benzoates / Astatine / Radiopharmaceuticals / Guanidine / ErbB Receptors / Antibodies, Monoclonal Limits: Animals Language: En Journal: Nucl Med Biol Journal subject: BIOLOGIA / MEDICINA NUCLEAR Year: 2003 Document type: Article Affiliation country: United States Country of publication: United States

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