Role of radical formation at tyrosine 193 in the allene oxide synthase domain of a lipoxygenase-AOS fusion protein from coral.

Wu, Fayi; Katsir, Leron J; Seavy, Margaret; Gaffney, Betty J

Wu, Fayi; Katsir, Leron J; Seavy, Margaret; Gaffney, Betty J.

Affiliation

Wu F; Department of Biological Science, Florida State University, Tallahassee, Florida 32306-4370, USA.

Biochemistry ; 42(22): 6871-80, 2003 Jun 10.

Article in En | MEDLINE | ID: mdl-12779342

Subject(s)

Cnidaria/enzymology; Free Radicals/chemistry; Intramolecular Oxidoreductases/chemistry; Intramolecular Oxidoreductases/metabolism; Lipoxygenase/chemistry; Lipoxygenase/metabolism; Recombinant Fusion Proteins/chemistry; Recombinant Fusion Proteins/metabolism; Tyrosine/chemistry; Amino Acid Sequence; Amino Acid Substitution; Animals; Catalase/genetics; Deuterium; Electron Spin Resonance Spectroscopy; Fatty Acids, Unsaturated/chemistry; Fatty Acids, Unsaturated/metabolism; Free Radicals/metabolism; Hydrogen Peroxide/metabolism; Intramolecular Oxidoreductases/genetics; Leukotrienes/metabolism; Lipoxygenase/genetics; Oxidation-Reduction; Peracetic Acid/chemistry; Peracetic Acid/pharmacology; Protein Structure, Tertiary; Recombinant Fusion Proteins/genetics; Reference Values; Substrate Specificity; Tyrosine/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Tyrosine / Recombinant Fusion Proteins / Lipoxygenase / Cnidaria / Intramolecular Oxidoreductases / Free Radicals Limits: Animals Language: En Journal: Biochemistry Year: 2003 Document type: Article Affiliation country: United States Country of publication: United States

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