Anti-Inflammatory Agents, Non-Steroidal/antagonists & inhibitors; Anti-Inflammatory Agents, Non-Steroidal/toxicity; Colorectal Neoplasms/metabolism; Polyamines/pharmacology; Anti-Inflammatory Agents, Non-Steroidal/administration & dosage; Anti-Inflammatory Agents, Non-Steroidal/metabolism; Apoptosis/drug effects; Cell Division/drug effects; Cell Membrane/drug effects; Cell Survival/drug effects; Colorectal Neoplasms/chemistry; Colorectal Neoplasms/pathology; DNA Fragmentation/drug effects; Dose-Response Relationship, Drug; Fluorescent Dyes/metabolism; Humans; Indoles/metabolism; Intercalating Agents/metabolism; Naproxen/administration & dosage; Naproxen/antagonists & inhibitors; Naproxen/metabolism; Naproxen/toxicity; Polyamines/metabolism; Putrescine/metabolism; Putrescine/pharmacology; Putrescine/physiology; Salicylates/administration & dosage; Salicylates/antagonists & inhibitors; Salicylates/metabolism; Salicylates/toxicity; Spermidine/metabolism; Spermidine/pharmacology; Spermidine/physiology; Spermine/metabolism; Spermine/pharmacology; Spermine/physiology; Sulindac/administration & dosage; Sulindac/antagonists & inhibitors; Sulindac/metabolism; Sulindac/toxicity; Tumor Cells, Cultured