Gonadotrope- and thyrotrope-specific expression of the human and bovine glycoprotein hormone alpha-subunit genes is regulated by distinct cis-acting elements.

Hamernik, D L; Keri, R A; Clay, C M; Clay, J N; Sherman, G B; Sawyer, H R; Nett, T M; Nilson, J H

Hamernik, D L; Keri, R A; Clay, C M; Clay, J N; Sherman, G B; Sawyer, H R; Nett, T M; Nilson, J H.

Affiliation

Hamernik DL; Department of Pharmacology, Case Western Reserve University School of Medicine, Cleveland, Ohio 44106.

Mol Endocrinol ; 6(10): 1745-55, 1992 Oct.

Article in En | MEDLINE | ID: mdl-1280329

Subject(s)

Glycoprotein Hormones, alpha Subunit/genetics; Gonadotropin-Releasing Hormone/pharmacology; Thyrotropin/pharmacology; Trans-Activators/metabolism; Triiodothyronine/pharmacology; Animals; Base Sequence; Brain/drug effects; Brain/metabolism; Cattle; Chloramphenicol O-Acetyltransferase/genetics; Chloramphenicol O-Acetyltransferase/metabolism; Estradiol/pharmacology; Female; Glycoprotein Hormones, alpha Subunit/biosynthesis; Humans; Liver/drug effects; Liver/metabolism; Mice; Mice, Transgenic; Molecular Sequence Data; Oligodeoxyribonucleotides; Ovariectomy; Pituitary Gland/drug effects; Pituitary Gland/metabolism; Polymerase Chain Reaction/methods; Promoter Regions, Genetic; Propylthiouracil/pharmacology; Recombinant Fusion Proteins/metabolism; beta-Galactosidase/genetics; beta-Galactosidase/metabolism

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Collection: 01-internacional Database: MEDLINE Main subject: Triiodothyronine / Thyrotropin / Glycoprotein Hormones, alpha Subunit / Trans-Activators / Gonadotropin-Releasing Hormone Limits: Animals / Female / Humans Language: En Journal: Mol Endocrinol Journal subject: BIOLOGIA MOLECULAR / ENDOCRINOLOGIA Year: 1992 Document type: Article Country of publication: United States

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