Cutting edge: link between innate and adaptive immunity: Toll-like receptor 2 internalizes antigen for presentation to CD4+ T cells and could be an efficient vaccine target.

Schjetne, Karoline W; Thompson, Keith M; Nilsen, Nadra; Flo, Trude H; Fleckenstein, Burkhard; Iversen, Jens-Gustav; Espevik, Terje; Bogen, Bjarne

Schjetne, Karoline W; Thompson, Keith M; Nilsen, Nadra; Flo, Trude H; Fleckenstein, Burkhard; Iversen, Jens-Gustav; Espevik, Terje; Bogen, Bjarne.

Affiliation

Schjetne KW; Institute of Immunology, University of Oslo, Rikshospitalet, Oslo, Norway. k.w.schjetne@labmed.uio.no

J Immunol ; 171(1): 32-6, 2003 Jul 01.

Article in En | MEDLINE | ID: mdl-12816980

Subject(s)

Antigen Presentation; Antigens/metabolism; Bacterial Vaccines/immunology; CD4-Positive T-Lymphocytes/immunology; CD4-Positive T-Lymphocytes/metabolism; Endocytosis/immunology; Membrane Glycoproteins/metabolism; Receptors, Cell Surface/metabolism; Amino Acid Sequence; Antibodies, Monoclonal/metabolism; Antibodies, Monoclonal/pharmacology; Antibody Specificity; Antigen Presentation/genetics; Antigen-Presenting Cells/cytology; Antigen-Presenting Cells/immunology; Antigen-Presenting Cells/metabolism; Antigens/genetics; Cell Line; Clone Cells; Endocytosis/genetics; Endosomes/immunology; Endosomes/metabolism; Epitopes, T-Lymphocyte/metabolism; Humans; Immunity, Active; Immunity, Innate; Immunoglobulin Constant Regions/metabolism; Immunoglobulin kappa-Chains/metabolism; Ligands; Membrane Glycoproteins/genetics; Membrane Glycoproteins/immunology; Molecular Sequence Data; Receptors, Cell Surface/genetics; Receptors, Cell Surface/immunology; Toll-Like Receptor 2; Toll-Like Receptors

Search on Google

Add to My VHL

XML

PubMed Links

Collection: 01-internacional Database: MEDLINE Main subject: Membrane Glycoproteins / Bacterial Vaccines / CD4-Positive T-Lymphocytes / Antigen Presentation / Receptors, Cell Surface / Endocytosis / Antigens Limits: Humans Language: En Journal: J Immunol Year: 2003 Document type: Article Affiliation country: Norway Country of publication: United States

Search on Google

Add to My VHL

XML

PubMed Links