[T-cell immunity and immunomodulators in the comprehensive treatment of diffuse toxic goiter]. / Sostoianie T-sistemy immuniteta i primenenie immunomoduliatorov v kompleksnom lechenii bol'nykh diffuznym toksicheskim zobom.
Ross Med Zh
; (5-12): 19-24, 1992.
Article
in Ru
| MEDLINE
| ID: mdl-1286263
ABSTRACT
Age-specific and related to DTG severity lowering of T-lymphocyte count, active and autologous T-lymphocyte number, thymic serum activity were found in 83 DTG patients. These shifts made justified the use of immunomodulator tactivin in 32 DTG patients. The drug was administered in daily subcutaneous doses (1 ml of 0.01% solution) for 5 days. As a result, the T-cell immunity returned to normal values. The highest response occurred in young subjects with moderate hyperthyroidism. Because a single tactivin course failed to bring up a persistent effect, repeat courses are needed to achieve good clinical and immunologic responses.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Peptides
/
Thymus Extracts
/
T-Lymphocytes
/
Adjuvants, Immunologic
/
Goiter
Limits:
Adult
/
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Language:
Ru
Journal:
Ross Med Zh
Journal subject:
MEDICINA
Year:
1992
Document type:
Article