A possible target of antioxidative therapy for diabetic vascular complications-vascular NAD(P)H oxidase.

Inoguchi, T; Tsubouchi, H; Etoh, T; Kakimoto, M; Sonta, T; Utsumi, H; Sumimoto, H; Yu, H Y; Sonoda, N; Inuo, M; Sato, N; Sekiguchi, N; Kobayashi, K; Nawata, H

Inoguchi, T; Tsubouchi, H; Etoh, T; Kakimoto, M; Sonta, T; Utsumi, H; Sumimoto, H; Yu, H Y; Sonoda, N; Inuo, M; Sato, N; Sekiguchi, N; Kobayashi, K; Nawata, H.

Affiliation

Inoguchi T; Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan. toyoshi@intmed3.med.kyushu-u.ac.jp

Curr Med Chem ; 10(17): 1759-64, 2003 Sep.

Article in En | MEDLINE | ID: mdl-12871120

Subject(s)

Antioxidants/therapeutic use; Diabetic Angiopathies/drug therapy; NADPH Oxidases/antagonists & inhibitors; Animals; Antioxidants/metabolism; Diabetic Angiopathies/enzymology; Endothelium, Vascular/drug effects; Endothelium, Vascular/enzymology; Enzyme Activation/drug effects; Enzyme Inhibitors/therapeutic use; Glucose/pharmacology; Humans; NADPH Oxidases/metabolism; Protein Kinase C/antagonists & inhibitors; Protein Kinase C/pharmacology; Reactive Oxygen Species/metabolism

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Collection: 01-internacional Database: MEDLINE Main subject: NADPH Oxidases / Diabetic Angiopathies / Antioxidants Limits: Animals / Humans Language: En Journal: Curr Med Chem Journal subject: QUIMICA Year: 2003 Document type: Article Affiliation country: Japan Country of publication: United Arab Emirates

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