HIP/PAP stimulates liver regeneration after partial hepatectomy and combines mitogenic and anti-apoptotic functions through the PKA signaling pathway.

Simon, Marie-Therese; Pauloin, Alain; Normand, Guillaume; Lieu, Hanh-Tu; Mouly, Helene; Pivert, Gerard; Carnot, Françoise; Tralhao, J Guilherme; Brechot, Christian; Christa, Laurence

Simon, Marie-Therese; Pauloin, Alain; Normand, Guillaume; Lieu, Hanh-Tu; Mouly, Helene; Pivert, Gerard; Carnot, Françoise; Tralhao, J Guilherme; Brechot, Christian; Christa, Laurence.

Affiliation

Simon MT; Institut National de la Santé et de la Recherche Médicale U-370, Necker-Pasteur Institutes, Universite Paris V, 75742 Paris Cedex 15, France.

FASEB J ; 17(11): 1441-50, 2003 Aug.

Article in En | MEDLINE | ID: mdl-12890698

Subject(s)

Antigens, Neoplasm/physiology; Apoptosis; Biomarkers, Tumor/physiology; Cyclic AMP-Dependent Protein Kinases/metabolism; Lectins, C-Type/physiology; Liver Regeneration; Proteins; Signal Transduction; Animals; Antigens, Neoplasm/genetics; Biomarkers, Tumor/genetics; Carrier Proteins/chemistry; Carrier Proteins/metabolism; Cells, Cultured; Cyclic AMP/metabolism; DNA/biosynthesis; Dactinomycin/toxicity; Hepatectomy; Hepatocytes/metabolism; Humans; Lectins, C-Type/genetics; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mitogens/physiology; Pancreatitis-Associated Proteins; Phosphorylation; Serine/metabolism; Tumor Necrosis Factor-alpha/toxicity; bcl-Associated Death Protein

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Collection: 01-internacional Database: MEDLINE Main subject: Signal Transduction / Proteins / Biomarkers, Tumor / Apoptosis / Cyclic AMP-Dependent Protein Kinases / Lectins, C-Type / Liver Regeneration / Antigens, Neoplasm Limits: Animals / Humans Language: En Journal: FASEB J Journal subject: BIOLOGIA / FISIOLOGIA Year: 2003 Document type: Article Affiliation country: France Country of publication: United States

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