Do cell culture conditions influence the carrier-mediated transport of peptides in Caco-2 cell monolayers?

Behrens, Isabel; Kissel, Thomas

Behrens, Isabel; Kissel, Thomas.

Affiliation

Behrens I; Department of Pharmaceutics and Biopharmacy, University of Marburg, Philipps-University, Ketzerbach 63, D-35032, Marburg/Lahn, Germany.

Eur J Pharm Sci ; 19(5): 433-42, 2003 Aug.

Article in En | MEDLINE | ID: mdl-12907294

Subject(s)

Carrier Proteins/metabolism; Peptides/metabolism; Symporters; ATP Binding Cassette Transporter, Subfamily B, Member 1/biosynthesis; ATP Binding Cassette Transporter, Subfamily B, Member 1/genetics; Actins/metabolism; Algorithms; Biological Transport, Active; Caco-2 Cells; Carrier Proteins/biosynthesis; Carrier Proteins/genetics; Cell Membrane/metabolism; Cephradine/metabolism; Culture Media; Electric Impedance; Fluorescein-5-isothiocyanate; Fluorescent Dyes; Humans; Microscopy, Confocal; Peptide Transporter 1; RNA, Messenger/biosynthesis; RNA, Messenger/isolation & purification; Reverse Transcriptase Polymerase Chain Reaction; Tight Junctions/drug effects

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Collection: 01-internacional Database: MEDLINE Main subject: Peptides / Carrier Proteins / Symporters Limits: Humans Language: En Journal: Eur J Pharm Sci Journal subject: FARMACIA / FARMACOLOGIA / QUIMICA Year: 2003 Document type: Article Affiliation country: Germany

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