Insulin resistance in obese boys with acanthosis nigricans.
Acta Paediatr Hung
; 32(4): 325-32, 1992.
Article
in En
| MEDLINE
| ID: mdl-1304190
ABSTRACT
Insulin resistance was investigated in three obese boys with acanthosis nigricans and their results were compared to those obtained in non-acanthotic obese patients. Blood glucose immune reactive serum insulin and C-peptide during oral glucose tolerance test and 125I-insulin binding investigated. Obese patients with acanthosis nigricans were more insulin resistant than simple obese controls. Insulin binding studies performed in two acanthotic patients suggested that one of them had insulin resistance type A, and the second patient had insulin resistance type B. According to the results acanthosis nigricans can serve as a marker for severe insulin resistance in obesity.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Insulin Resistance
/
Acanthosis Nigricans
/
Obesity
Limits:
Adolescent
/
Child
/
Humans
/
Male
Language:
En
Journal:
Acta Paediatr Hung
Year:
1992
Document type:
Article