Overexpression of H-ras oncogene induces resistance to the growth-inhibitory action of transforming growth factor beta-1 (TGF-beta 1) and alters the number and type of TGF-beta 1 receptors in rat intestinal epithelial cell clones.

Filmus, J; Zhao, J; Buick, R N

Filmus, J; Zhao, J; Buick, R N.

Affiliation

Filmus J; Ontario Cancer Institute, University of Toronto, Ontario, Canada.

Oncogene ; 7(3): 521-6, 1992 Mar.

Article in En | MEDLINE | ID: mdl-1312703

Subject(s)

Genes, ras; Intestinal Mucosa/metabolism; Proto-Oncogene Proteins p21(ras)/genetics; Receptors, Cell Surface/physiology; Transforming Growth Factor beta/pharmacology; Animals; Cell Division; Cell Transformation, Neoplastic/metabolism; Cell Transformation, Neoplastic/pathology; Clone Cells; Gene Expression; Growth Inhibitors; In Vitro Techniques; Intestinal Mucosa/cytology; Rats; Receptors, Transforming Growth Factor beta

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Collection: 01-internacional Database: MEDLINE Main subject: Proto-Oncogene Proteins p21(ras) / Transforming Growth Factor beta / Genes, ras / Receptors, Cell Surface / Intestinal Mucosa Limits: Animals Language: En Journal: Oncogene Journal subject: BIOLOGIA MOLECULAR / NEOPLASIAS Year: 1992 Document type: Article Affiliation country: Canada Country of publication: United kingdom

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