Epidemiology of Pseudomonas aeruginosa in an intensive care unit using selective decontamination of the digestive tract.
J Hosp Infect
; 20(3): 199-208, 1992 Mar.
Article
in En
| MEDLINE
| ID: mdl-1348775
ABSTRACT
Selective decontamination of the digestive tract (SDD) aims to reduce the rate of nosocomial infections in critical care patients. Pseudomonas spp. are common nosocomial pathogens and in this study isolates collected from patients and the environment during an SDD trial were examined. The study enrolled 161 SDD cases and 170 controls. Pseudomonads were isolated from 27% of SDD patients and 30% of controls. SDD partially suppressed colonization in the 'gastro-respiratory' mucosae but not in the rectum. A total of 108 isolates of pseudomonads were recovered from the environment. Resistance in rectal isolates was minimal but isolates from 'gastro-respiratory' sites showed increasing aminoglycoside resistance. Eighty-six per cent of aminoglycoside-resistant isolates from both patient groups and environment were pyocine type 1x. Episodes of infection were reduced in the SDD patients (6) compared with the controls (16), aminoglycoside-resistant strains being associated with zero episodes in SDD patients but with five in the control group.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Pseudomonas aeruginosa
/
Disinfection
/
Cross Infection
/
Digestive System
/
Intensive Care Units
Type of study:
Clinical_trials
/
Screening_studies
Limits:
Humans
Language:
En
Journal:
J Hosp Infect
Year:
1992
Document type:
Article
Affiliation country:
United kingdom