Monoclonal autoantibodies to subnucleosomes from a MRL/Mp(-)+/+ mouse. Oligoclonality of the antibody response and recognition of a determinant composed of histones H2A, H2B, and DNA.

Losman, M J; Fasy, T M; Novick, K E; Monestier, M

Losman, M J; Fasy, T M; Novick, K E; Monestier, M.

Affiliation

Losman MJ; Garden State Cancer Center, Newark, NJ 07103.

J Immunol ; 148(5): 1561-9, 1992 Mar 01.

Article in En | MEDLINE | ID: mdl-1371530

Subject(s)

Antibodies, Monoclonal/immunology; Autoantibodies/immunology; Autoimmune Diseases/immunology; DNA/immunology; Epitopes/analysis; Histones/immunology; Nucleosomes/immunology; Amino Acid Sequence; Animals; Antibodies, Monoclonal/genetics; Antibody Specificity; Autoantibodies/genetics; Base Sequence; Female; Genes, Immunoglobulin; Immunoglobulin Variable Region/genetics; Lupus Nephritis/immunology; Mice; Molecular Sequence Data; Mutation

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Collection: 01-internacional Database: MEDLINE Main subject: Autoantibodies / Autoimmune Diseases / DNA / Histones / Nucleosomes / Antibodies, Monoclonal / Epitopes Limits: Animals Language: En Journal: J Immunol Year: 1992 Document type: Article Country of publication: United States

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