[Clinical significance of the measurement of serum pepsinogen group I and II by enzyme-linked immunosorbent assay].
Rinsho Byori
; 40(9): 977-81, 1992 Sep.
Article
in Ja
| MEDLINE
| ID: mdl-1434035
ABSTRACT
We have developed enzyme-linked immunosorbent assay (ELISA) for pepsinogen group I and II (PG I.II) in human serum, and clinical significance of serum pepsinogen measurement was evaluated. Serum PG I.II levels in patients with gastric and duodenal ulcer were higher than those in normal healthy subjects. On the other hand, serum PG I levels in patients with pernicious anemia were significantly low levels. In both gastric ulcer and duodenal ulcer, serum PG I.II levels at active stage were higher than healing stage. These results suggested that the measurement of PG I.II levels was useful for screening or monitoring test for the injury of gastric and duodenal mucosa.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Pepsinogens
/
Enzyme-Linked Immunosorbent Assay
/
Biomarkers
Type of study:
Diagnostic_studies
Limits:
Adolescent
/
Adult
/
Aged
/
Child
/
Female
/
Humans
/
Male
/
Middle aged
Language:
Ja
Journal:
Rinsho Byori
Year:
1992
Document type:
Article