Selecting T cell receptors with high affinity for self-MHC by decreasing the contribution of CD8.

Sherman, L A; Hesse, S V; Irwin, M J; La Face, D; Peterson, P

Sherman, L A; Hesse, S V; Irwin, M J; La Face, D; Peterson, P.

Affiliation

Sherman LA; Department of Immunology, Scripps Research Institute, La Jolla, CA 92037.

Science ; 258(5083): 815-8, 1992 Oct 30.

Article in En | MEDLINE | ID: mdl-1439792

Subject(s)

CD8 Antigens/immunology; Histocompatibility Antigens Class I/immunology; Immune Tolerance; Receptors, Antigen, T-Cell/immunology; Animals; Antigens, Viral/immunology; H-2 Antigens/genetics; H-2 Antigens/immunology; HLA-A2 Antigen/genetics; HLA-A2 Antigen/immunology; Humans; Influenza A virus/immunology; Mice; Mice, Transgenic; T-Lymphocytes, Cytotoxic/immunology; Thymus Gland/growth & development; Thymus Gland/immunology

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Collection: 01-internacional Database: MEDLINE Main subject: Receptors, Antigen, T-Cell / Histocompatibility Antigens Class I / CD8 Antigens / Immune Tolerance Limits: Animals / Humans Language: En Journal: Science Year: 1992 Document type: Article Country of publication: United States

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