Twelve-month evaluation of the clinical pharmacokinetics of total and free mycophenolic acid and its glucuronide metabolites in renal allograft recipients on low dose tacrolimus in combination with mycophenolate mofetil.

Kuypers, D R J; Vanrenterghem, Y; Squifflet, J P; Mourad, M; Abramowicz, D; Oellerich, M; Armstrong, V; Shipkova, M; Daems, J

Kuypers, D R J; Vanrenterghem, Y; Squifflet, J P; Mourad, M; Abramowicz, D; Oellerich, M; Armstrong, V; Shipkova, M; Daems, J.

Affiliation

Kuypers DR; Department of Nephrology and Renal Transplantation, Catholic University of Leuven, Belgium. Dirk.kuyper@uz.kuleuven.ac.be

Ther Drug Monit ; 25(5): 609-22, 2003 Oct.

Article in En | MEDLINE | ID: mdl-14508385

Subject(s)

Glucuronates/pharmacokinetics; Immunosuppressive Agents/administration & dosage; Kidney Transplantation; Mycophenolic Acid/analogs & derivatives; Mycophenolic Acid/administration & dosage; Mycophenolic Acid/pharmacokinetics; Tacrolimus/administration & dosage; Adult; Aged; Area Under Curve; Drug Therapy, Combination; Female; Glucuronides; Graft Rejection/prevention & control; Humans; Immunosuppressive Agents/pharmacokinetics; Male; Middle Aged; Prospective Studies; Transplantation, Homologous

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Collection: 01-internacional Database: MEDLINE Main subject: Kidney Transplantation / Tacrolimus / Glucuronates / Immunosuppressive Agents / Mycophenolic Acid Type of study: Clinical_trials / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Adult / Aged / Female / Humans / Male / Middle aged Language: En Journal: Ther Drug Monit Year: 2003 Document type: Article Affiliation country: Belgium Country of publication: United States

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