Phage lytic enzyme Cpl-1 as a novel antimicrobial for pneumococcal bacteremia.

Loeffler, Jutta M; Djurkovic, Svetolik; Fischetti, Vincent A

Loeffler, Jutta M; Djurkovic, Svetolik; Fischetti, Vincent A.

Affiliation

Loeffler JM; Laboratory of Bacterial Pathogenesis, The Rockefeller University, New York, New York 10021, USA.

Infect Immun ; 71(11): 6199-204, 2003 Nov.

Article in En | MEDLINE | ID: mdl-14573637

Subject(s)

Anti-Bacterial Agents/therapeutic use; Bacteremia/drug therapy; Muramidase/therapeutic use; Pneumococcal Infections/drug therapy; Streptococcus Phages/enzymology; Animals; Bacteremia/mortality; Disease Models, Animal; Drug Resistance, Bacterial; Enzyme Stability; Female; Hydrogen-Ion Concentration; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Muramidase/immunology; Nasopharynx/microbiology; Pneumococcal Infections/mortality; Streptococcus pneumoniae/drug effects

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pneumococcal Infections / Muramidase / Bacteremia / Streptococcus Phages / Anti-Bacterial Agents Limits: Animals Language: En Journal: Infect Immun Year: 2003 Document type: Article Affiliation country: United States Country of publication: United States

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